Immunohistochemistry Kits and Reagents
ABclonal Technology YTHDC2 Rabbit pAb
This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3 UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
Medchemexpress LLC PDK1 Human sf9 Hi 50ug
PDK1 protein is a key kinase that controls glucose and fatty acid metabolism by phosphorylating pyruvate dehydrogenase subunits PDHA1 and PDHA2 This molecular switch inhibits pyruvate dehydrogenase fine-tunes metabolite flux and downregulates aerobic respiration PDK1 Protein Human (sf9 His) is the recombinant human-derived PDK1 protein expressed by Sf9 insect cells with N-His labeled tag
Cell Signaling Technology SignalStain Boost IHC Detection Reagent (HRP, Rabbit) 1 ml
SignalStain Boost IHC Detection Reagent (HRP, Rabbit) 1 ml
Abcam Mouse and Rabbit Specific HRP/AEC IHC Detection Kit - Micro-polymer, 125ML
This IHC detection kit is used to detect mouse and rabbit primary antibodies in immunohistochemistry (IHC).
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Phospho-PDK1/PDPK1-S241 Rabbit pAb
Enables 3-phosphoinositide-dependent protein kinase activity, phospholipase activator activity, and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway, regulation of protein kinase activity, and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection, cytosol, and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
Abcam DoubleStain IHC Kit: M&Rt on mouse tissue (BCIP & AEC), 60ML
Abcam's DoubleStain IHC Kit (ab183278) is designed to use with user supplied mouse and rat primary antibody to detect two distinct antigens on mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Seracare Life Sciences Inc BIOTIN-SA HRP KIT RB PRI AB
HistoMark Biotin Streptavidin-HRP Systems provide rapid, precise localization of cell surface and intracellular antigens in frozen or paraffin-embedded tissue, cytospins and touch preparations. These systems also facilitate double or triple labeleing experiments, as detection can be performed simultaneously with primary antibodies of different animal species. Streptavidin demonstrates less non-specific binding than avidin. Biotinylated anti-rabbit antibody is human serum adsorbed to minimize cross-reactivity.
Biolegend DAB Substrate Buffer with Stabilizer
DAB Substrate Buffer with Stabilizer Apps: IHC; Size: 2 x 50 ml
ABclonal Technology MAP2 Rabbit mAb
This gene encodes a protein that belongs to the microtubule-associated protein family The proteins of this family are thought to be involved in microtubule assembly which is an essential step in neurogenesis The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites implicating a role in determining and stabilizing dentritic shape during neuron development A number of alternatively spliced variants encoding distinct isoforms have been described
Medchemexpress LLC Recombinant rat discoidin domain receptor 1 (DDR1), C-terminal His tag | 5 UG
Recombinant rat discoidin domain receptor 1 (DDR1) protein expressed in HEK293 cells with a C-terminal His tag. The protein is intended for in vitro research of DDR1-mediated collagen binding and downstream signaling, including SRC and MAP kinase pathways, as well as matrix remodeling and cell migration. Supplied as a purified recombinant protein for biochemical and cell-based assays.
- Recombinant rat DDR1 expressed in HEK293 cells.
- C-terminal His tag for detection and purification.
- Supports studies of collagen binding and downstream signaling pathways.
- Suitable for biochemical assays and cell-based applications.
- Available in multiple microgram and milligram sizes for experimental flexibility.
Sigma Aldrich Fine Chemicals Biosciences Red-Gal(R) | 138182-21-5 | MFCD00467206 |
Red-Gal(R) | Mol Wt: 329.73 | 138182-21-5 | MFCD00467206 |
Biotium Cytokeratin 8(B22.1), Biotin conjugate, 0.1mg/mL
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant)
Biotium CD6(C6/372), CF594 conjugate, 0.1mg/mL
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.