Immunohistochemistry Kits and Reagents
Abcam TripleStain IHC Kit: M&M&R on Human tissue (DAB, AP/Red & HRP/Green), 60ML
Abcam's TripleStain IHC kit (ab183286) is designed to use with user supplied two mouse primary antibodies and one rabbit primary antibody to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Phospho-TDP-43/TARDBP-S409/S410 Rabbit pAb
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Biocare Medical, LLC Rodent Block R - 25 ml
Rodent Block R is an immunohistochemical reagent designed for blocking endogenous rat IgG and non-specific background in rat tissues and red blood cells. After the application of Rodent Block R, a mouse monoclonal antibody can be applied. It can also be used on an automated staining system.
Biotium Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2921), CF740 conjugate, 0.1mg/mL
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like
AGILENT TECHNOLOGIES DAKO INVISION FLEX MOUSE LINKER
NC3842196 INVISION FLEX MOUSE LINKER
Biotium CD36(1E8), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 80 kDa-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue
OriGene Desmin (DES) CytoSection, Positive Control For IHC, ICC, & ISH, 25 Slides
The Origene Technologies Desmin (DES) CytoSection is a crucial tool for researchers, providing validated positive controls for detecting Desmin expression in immunohistochemical, immunocytochemical, and *in situ* hybridization applications. This product includes 25 FFPE slides containing HEK293T cells with transient overexpression of human Desmin, ensuring reliable and accurate experimental results, distinguishing it from other controls with its specific targeted application.
Abcam 2 mm Sagittal Mouse Brain Slicer, 1UNIT
This 2 mm Sagittal mouse brain slicer (ab243313) allows you to easily cut a brain into smaller pieces for easier imaging with objectives that have a limited working distance.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Phospho-β-Catenin-S675 Rabbit pAb
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.